The International Journal of Developmental Biology

Int. J. Dev. Biol. 57: 133 - 139 (2013)

Vol 57, Issue 2-3-4

Special Issue: Male Germ Cells in Development & Tumors

Classification, epidemiology and therapies for testicular germ cell tumours

Published: 30 May 2013

Nikhil Vasdev*, Andrew Moon and Andrew C. Thorpe

Department of Urology, Freeman Hospital, Newcastle upon Tyne, United Kingdom


Testicular germ cell tumours (TGCT) account for between 1% and 1.5% of male neoplasms and 5% of urological tumours in general. They are classified broadly into Seminoma, which resemble primordial germ cells (PGCs), and Non-Seminoma, which are either undifferentiated (embryonal carcinoma) or differentiated (exhibiting a degree of embryonic (teratoma) or extra-embryonic (yolk sac choriocarcinoma) patterning). We present the current details of the latest classification, epidemiology and treatment aspects of TGCT in the UK in our review.


classification, epidemiology, therapy, testicular germ cell tumor, prognosis

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