The International Journal of Developmental Biology

Volume 63 > Issue 3-4-5 (Special Issue)

Cover Vol. 63 N. 3-4-5

Early mammalian development

Edited by: Aneta Suwinska and Anna Ajduk

Cover Legend

Mouse preimplantation embryos at various stages of development immunofluorescently stained for the presence of lineage-specific markers, DNA (blue) and F-actin (green). Top left: 16-cell embryo stained for the presence of F-actin and pERM (yellow). Top right: early blastocyst revealing the location of F-actin and the trophectoderm marker Cdx2 (red). Bottom: late blastocyst fluorescently labeled with the trophectoderm marker Cdx2 (red), the epiblast marker Sox2 (white) and the primitive endoderm marker Sox17 (green). DNA was labeled with Draq5.



Early mammalian development: from basic research to the clinic

Aneta Suwińska and Anna Ajduk

Int. J. Dev. Biol. (2019) 63: 73-75

Introductory Papers

Breakthroughs and challenges of modern developmental biology and reproductive medicine

Simon Fishel, Anna-Katerina Hadjantonakis, Berenika Plusa, Laura Rienzi, Yojiro Yamanaka, Aneta Suwińska and Anna Ajduk

Int. J. Dev. Biol. (2019) 63: 77-82

A short history of in vitro fertilization (IVF)

Martin H. Johnson

Int. J. Dev. Biol. (2019) 63: 83-92


Mitochondria and lipid metabolism in mammalian oocytes and early embryos

Josephine Bradley and Karl Swann

Int. J. Dev. Biol. (2019) 63: 93-103

Function of atypical mammalian oocyte/zygote nucleoli and its implications for reproductive biology and medicine

Josef Fulka, Jr., Michal Benc, Pasqualino Loi, Alena Langerova and Helena Fulka

Int. J. Dev. Biol. (2019) 63: 105-112

Regulation of the cell cycle in early mammalian embryos and its clinical implications

Lenka Radonova, Tereza Svobodova and Martin Anger

Int. J. Dev. Biol. (2019) 63: 113-122

Somatic cell nuclear transfer: failures, successes and the challenges ahead

Marta Czernik, Debora A. Anzalone, Luca Palazzese, Mami Oikawa and Pasqualino Loi

Int. J. Dev. Biol. (2019) 63: 123-130

Computational models for the dynamics of early mouse embryogenesis

Alen Tosenberger, Didier Gonze, Claire Chazaud and Geneviève Dupont

Int. J. Dev. Biol. (2019) 63: 131-142

Multiplying embryos: experimental monozygotic polyembryony in mammals and its uses

Ellen Casser, Steffen Israel and Michele Boiani

Int. J. Dev. Biol. (2019) 63: 143-155

The mammalian embryo’s first agenda: making trophectoderm

Eszter Posfai, Isidora Rovic and Andrea Jurisicova

Int. J. Dev. Biol. (2019) 63: 157-170

FGF/ERK signaling pathway: how it operates in mammalian preimplantation embryos and embryo-derived stem cells

Anna Soszyńska, Katarzyna Klimczewska and Aneta Suwińska

Int. J. Dev. Biol. (2019) 63: 171-186

Beyond the mouse: non-rodent animal models for study of early mammalian development and biomedical research

Zofia E. Madeja, Piotr Pawlak and Anna Piliszek

Int. J. Dev. Biol. (2019) 63: 187-201

Test-tube embryos - mouse and human development in vitro to blastocyst stage and beyond

Niraimathi Govindasamy, Binyamin Duethorn, Hatice O. Oezgueldez, Yung S. Kim and Ivan Bedzhov

Int. J. Dev. Biol. (2019) 63: 203-215

Assessing the epigenetic risks of assisted reproductive technologies: a way forward

Federica Zacchini, Silvestre Sampino, Adrian M. Stankiewicz, Thomas Haaf and Grazyna E. Ptak

Int. J. Dev. Biol. (2019) 63: 217-222

Diverse developmental strategies of X chromosome dosage compensation in eutherian mammals

Alexander I. Shevchenko, Elena V. Dementyeva, Irina S. Zakharova and Suren M. Zakian

Int. J. Dev. Biol. (2019) 63: 223-233

Light microscopy of mammalian gametes and embryos: methods and applications

Anna Ajduk and Maciej Szkulmowski

Int. J. Dev. Biol. (2019) 63: 235-244

Original Article

Chromatin organization and timing of polar body I extrusion identify developmentally competent mouse oocytes

Federica Cavalera, Mario Zanoni, Valeria Merico, Lucia Sacchi, Riccardo Bellazzi, Silvia Garagna and Maurizio Zuccotti

Int. J. Dev. Biol. (2019) 63: 245-251

Technical Report

Enucleolation and nucleolus transfer in mammalian oocytes and zygotes

Michal Benc, Josef Fulka, Jr., František Strejček, Martin Morovič, Matej Murín, Stanislava Martínková, Dominika Jettmarová and Jozef Laurinčík

Int. J. Dev. Biol. (2019) 63: 253-258