The International Journal of Developmental Biology

Volume 54 > Issue 11-12 (Special Issue)

Cover Vol. 54 N. 11-12

Animal Cloning & Cell Reprogramming

Edited by: Michele Boiani and José B. Cibell

Cover Legend

(Clockwise order from top-left): (1) Unfertilized eggs of the zebrafish (Danio rerio) (10X objective lens); (2) Transplantation of a cumulus cell nucleus into a mouse metaphase II oocyte deprived of its maternal chromosomes (40X objective lens); (3) Two cloned mouse pups and their placentae a few minutes after birth by caesarean section; note the still hypoxic complexion, which will recover as soon as the pups start breathing; (4) Neuronal rosettes from induced pluripotent stem (iPS) cells obtained from human fibroblasts (10X objective lens) and (5) Cloned mouse blastocysts after in situ hybridization with a riboprobe for the Nanog gene; note the purple hybridization signal localized to the inner cell mass (10X objective lens). In the background: undifferentiated mouse embryonic stem (ES) cell colonies growing on a carpet of mouse embryonic fibroblasts (MEFs) and expressing the Oct4-GFP transgene.



What scientists would like to tell you about reprogramming (if only they knew!)

Michele Boiani and José B. Cibelli

Int. J. Dev. Biol. (2010) 54: 1541-1543

Natural programming and basic principles of reprogramming

Natural and artificial routes to pluripotency

Winfried H. Krueger, Lindsey C. Swanson, Borko Tanasijevic and Theodore P. Rasmussen

Int. J. Dev. Biol. (2010) 54: 1545-1564

DNA methylation reprogramming and DNA repair in the mouse zygote

Konstantin Lepikhov, Mark Wossidlo, Julia Arand and Jörn Walter

Int. J. Dev. Biol. (2010) 54: 1565-1574

Reprogramming cell fate to pluripotency: the decision-making signalling pathways

Daniela Sanges and Maria-Pia Cosma

Int. J. Dev. Biol. (2010) 54: 1575-1587

Structure and functions of powerful transactivators: VP16, MyoD and FoxA

Hiroyuki Hirai, Tetsuya Tani and Nobuaki Kikyo

Int. J. Dev. Biol. (2010) 54: 1589-1596

Animal cloning

Virus, development and pluripotent stem cells - an interview with Rudolf Jaenisch

José B. Cibelli

Int. J. Dev. Biol. (2010) 54: 1597-1607

Faithful reprogramming to pluripotency in mammals - what does nuclear transfer teach us?

Julien Maruotti, Alice Jouneau and Jean-Paul Renard

Int. J. Dev. Biol. (2010) 54: 1609-1621

Role of the donor nuclei in cloning efficiency: can the ooplasm reprogram any nucleus?

Yoko Kato and Yukio Tsunoda

Int. J. Dev. Biol. (2010) 54: 1623-1629

Nuclear reprogramming in zygotes

Chanchao Lorthongpanich, Davor Solter and Chin Yan Lim

Int. J. Dev. Biol. (2010) 54: 1631-1640

Improvement of mouse cloning using nuclear transfer-derived embryonic stem cells and/or histone deacetylase inhibitor

Sayaka Wakayama and Teruhiko Wakayama

Int. J. Dev. Biol. (2010) 54: 1641-1648

Enhancing somatic nuclear reprogramming by Oct4 gain-of-function in cloned mouse embryos

Martin J. Pfeiffer, Sebastian T. Balbach, Telma C. Esteves, Nicola Crosetto and Michele Boiani

Int. J. Dev. Biol. (2010) 54: 1649-1657

Role of mitochondrial DNA replication during differentiation of reprogrammed stem cells

Richard D.W. Kelly and Justin C. St. John

Int. J. Dev. Biol. (2010) 54: 1659-1670

Cloning of non-human primates: the road "less traveled by"

Michelle L. Sparman, Masahito Tachibana and Shoukhrat M. Mitalipov

Int. J. Dev. Biol. (2010) 54: 1671-1678

The influence of donor nucleus source on the outcome of zebrafish somatic cell nuclear transfer

Kannika Siripattarapravat, Boonya Pinmee, Eun-Ah Chang, Juan D. Muñoz, Koichi Kawakami and José B. Cibelli

Int. J. Dev. Biol. (2010) 54: 1679-1683

Cell reprograming

Reprogramming cell fate: a scientific journey from viral enhancers to the master gene regulator Oct4 - an interview with Hans R. Schöler

Michele Boiani

Int. J. Dev. Biol. (2010) 54: 1685-1695

Kinetics of reprogramming in cell fusion hybrids

Hyun-Woo Choi and Jeong-Tae Do

Int. J. Dev. Biol. (2010) 54: 1697-1702


Porcine induced pluripotent stem cells analogous to naïve and primed embryonic stem cells of the mouse

Bhanu Prakash V.L. Telugu, Toshihiko Ezashi and R. Michael Roberts

Int. J. Dev. Biol. (2010) 54: 1703-1711

Exploring refined conditions for reprogramming cells by recombinant Oct4 protein

Marc Thier, Bernhard Münst and Frank Edenhofer

Int. J. Dev. Biol. (2010) 54: 1713-1721

Comparison of reprogramming ability of mouse ES and iPS cells measured by somatic cell fusion

Huseyin Sumer, Craig Nicholls, Jun Liu, Pollyanna A. Tat, Jun-Ping Liu and Paul J. Verma

Int. J. Dev. Biol. (2010) 54: 1723-1728

Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells

Alessandro Prigione and James Adjaye

Int. J. Dev. Biol. (2010) 54: 1729-1741


Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells

Sakthikumar Ambady, Christopher Malcuit, Olga Kashpur, Denis Kole, William F. Holmes, Emmett Hedblom, Raymond L. Page and Tanja Dominko

Int. J. Dev. Biol. (2010) 54: 1743-1754

Two paternal genomes are compatible with dopaminergic in vitro and in vivo differentiation

Soon Won Choi, Sigrid Eckardt, Ruhel Ahmad, Wanja Wolber, K. John McLaughlin, Anna-Leena Sirén and Albrecht M. Müller

Int. J. Dev. Biol. (2010) 54: 1755-1762