The International Journal of Developmental Biology

Int. J. Dev. Biol. 49: 85 - 103 (2005)

Vol 49, Issue 2-3

Special Issue: The Nogent Institute

The Nogent Institute - 50 Years of Embryology

Published: 1 May 2005

Nicole Le Douarin*

Laboratoire d'Embryologie Cellulaire et Moléculaire, CNRS UMR 7128, Nogent-sur-Marne, France


The Nogent Institute, founded by Etienne Wolff in 1955, was dedicated to the study of the avian model. The quail-chick chimera marking system, devised in 1969, gave a new impetus to the analysis of cell migrations and interactions in the developing nervous, immune and hematopoietic systems. These studies, still very active, have been extended by various groups the world over.


quail-chick chimera, neural crest, central nervous system, immune tolerance, hemangioblast

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