Edited by: Charles Durand,Tierry Jaffredo and Alexander Medvinsky
The beautiful drawing at the center represents a cross section through the area vasculosa of a 5 somite (embryonic day 8.5) rabbit embryo depicting a vessel formed by endothelial cells (Ed) within which primitive blood cells (pBlz) circulate. Two endothelial cells are changing their phenotype to give rise to round, hematopoietic cells (m). The endothelium is surrounded by a thin layer of cells designated as mesenchymal (x). Taken from Alexander A. Maximov (1909) Arch. Mikr. Anat. Entwickslungs. 73: 444-561. Encircling the drawing are the models elaborated upon in the present issue. Starting from the top to right: erythroid colony from mouse embryonic aorta (M. Souyri); E11.5 mouse embryo stained to reveal the vascular network (M. Souyri); Xenopus embryo, Stage 32 tail bud stage (V. Belo); zebrafish embryo (F. Giudicelli), 48hpf; Drosophila larva (F. Peronnet). Human embryo, Carnegie stage 12, 25-27 days post ovulation (H. Etchevers); avian embryo, HH15, 50-53h of development (C. Pouget). Composition: Sophie Gournet.
Int. J. Dev. Biol. (2010) 54: 951-954
Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells
Int. J. Dev. Biol. (2010) 54: 955-964
OPEN ACCESS
Int. J. Dev. Biol. (2010) 54: 965-990
Dissecting hematopoietic differentiation using the embryonic stem cell differentiation model
Int. J. Dev. Biol. (2010) 54: 991-1002
Int. J. Dev. Biol. (2010) 54: 1003-1009
Primitive erythropoiesis in the mammalian embryo
Int. J. Dev. Biol. (2010) 54: 1011-1018
Int. J. Dev. Biol. (2010) 54: 1019-1031
Primitive and definitive erythropoiesis in the yolk sac: a bird’s eye view
Int. J. Dev. Biol. (2010) 54: 1033-1043
Aortic remodelling during hemogenesis: is the chicken paradigm unique?
Int. J. Dev. Biol. (2010) 54: 1045-1054
Int. J. Dev. Biol. (2010) 54: 1055-1060
Embryonic origin of human hematopoiesis
Int. J. Dev. Biol. (2010) 54: 1061-1065
Int. J. Dev. Biol. (2010) 54: 1067-1074
The quest for hematopoietic stem cells in the embryo. An interview with Françoise Dieterlen-Lièvre
Int. J. Dev. Biol. (2010) 54: 1075-1078
Allantois and placenta as developmental sources of hematopoietic stem cells
Int. J. Dev. Biol. (2010) 54: 1079-1087
Hematopoietic stem cell development in the placenta
Int. J. Dev. Biol. (2010) 54: 1089-1098
Transcription factor interplay during Drosophila haematopoiesis
Int. J. Dev. Biol. (2010) 54: 1107-1115
Int. J. Dev. Biol. (2010) 54: 1117-1125
Genetic control of hematopoietic development in Xenopus and zebrafish
Int. J. Dev. Biol. (2010) 54: 1139-1149
Hematopoietic stem cell emergence in the conceptus and the role of Runx1
Int. J. Dev. Biol. (2010) 54: 1151-1163
Int. J. Dev. Biol. (2010) 54: 1165-1173
The Notch pathway in the developing hematopoietic system
Int. J. Dev. Biol. (2010) 54: 1175-1188
Int. J. Dev. Biol. (2010) 54: 1189-1200
Gene regulatory networks governing haematopoietic stem cell development and identity
Int. J. Dev. Biol. (2010) 54: 1201-1211