The International Journal of Developmental Biology

Volume 48 > Issue 8-9 (Special Issue)

Cover Vol. 48 N. 8-9

Eye Development

Edited by: Joram Piatigorsky and Robert Grainger

Cover Legend

"Seeing is what matters. Seeing must suffice." René Magritte (1898-1967, Belgium). In this 1935 version of the surrealist Le Faux Miroir (The False Mirror) first painted by René Magritte in 1928, the inverted iris/pupil acts as a mirror of the exterior world instead of being the mirror of the soul. In his art, Magritte used the unexpected to liberate our conventional vision from its obscurity, in order to glimpse the hidden mystery of the visible world. As Magritte says "Everything we see hides another thing".



Joram Piatigorsky and Robert M. Grainger

Int. J. Dev. Biol. (2004) 48: 685-686

Personal Views

The extracellular matrix in development and regeneration. An interview with Elizabeth D. Hay

Robert L. Trelstad

Int. J. Dev. Biol. (2004) 48: 687-694

A life in research on lens regeneration and transdifferentiation. An interview with Goro Eguchi

Kunio Yasuda

Int. J. Dev. Biol. (2004) 48: 695-700

Developmental Evolution of Visual Organs

Evolving eyes

Russell D. Fernald

Int. J. Dev. Biol. (2004) 48: 701-705

Historical perspective on the development and evolution of eyes and photoreceptors

Walter J. Gehring

Int. J. Dev. Biol. (2004) 48: 707-717


Cubozoan jellyfish: an Evo/Devo model for eyes and other sensory systems

Joram Piatigorsky and Zbynek Kozmik

Int. J. Dev. Biol. (2004) 48: 719-729

Blind cavefish and heat shock protein chaperones: a novel role for hsp90alpha in lens apoptosis

Thomas A. Hooven, Yoshiyuki Yamamoto and William R. Jeffery

Int. J. Dev. Biol. (2004) 48: 731-738

Embryonic Induction and Eye Specification

From embryonic induction to cell lineages: revisiting old problems for modern study

Tokindo S. Okada

Int. J. Dev. Biol. (2004) 48: 739-742


Conservation and non-conservation of genetic pathways in eye specification

Amy L. Donner and Richard L. Maas

Int. J. Dev. Biol. (2004) 48: 743-753

The little R cell that could

Raghavendra Nagaraj and Utpal Banerjee

Int. J. Dev. Biol. (2004) 48: 755-760

Regulation of vertebrate eye development by Rx genes

Travis J. Bailey, Heithem El-Hodiri, Li Zhang, Rina Shah, Peter H. Mathers and Milan Jamrich

Int. J. Dev. Biol. (2004) 48: 761-770

A re-examination of lens induction in chicken embryos: in vitro studies of early tissue interactions

Charles H. Sullivan, Leslie Braunstein, Royce M. Hazard-Leonards, Anna L. Holen, Fouad Samaha, Laurie Stephens and Robert M. Grainger

Int. J. Dev. Biol. (2004) 48: 771-782

Pathways regulating lens induction in the mouse

Richard A. Lang

Int. J. Dev. Biol. (2004) 48: 783-791

Analysis of mouse eye development with chimeras and mosaics

J. Martin Collinson, Robert E. Hill and John D. West

Int. J. Dev. Biol. (2004) 48: 793-804

Lens & Cornea Development

Lens differentiation and crystallin regulation: a chick model

Hasan M. Reza and Kunio Yasuda

Int. J. Dev. Biol. (2004) 48: 805-817


Interplay of Pax6 and SOX2 in lens development as a paradigm of genetic switch mechanisms for cell differentiation

Hisato Kondoh, Masanori Uchikawa and Yusuke Kamachi

Int. J. Dev. Biol. (2004) 48: 819-827

Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens

Ales Cvekl, Ying Yang, Bharesh K. Chauhan and Kveta Cveklova

Int. J. Dev. Biol. (2004) 48: 829-844

Contributions by members of the TGFbeta superfamily to lens development

David Beebe, Claudia Garcia, Xiaohui Wang, Ramya Rajagopal, Mary Feldmeier, Ji-Young Kim, Anna Chytil, Harold Moses, Ruth Ashery-Padan, and Michael Rauchman

Int. J. Dev. Biol. (2004) 48: 845-856

Regulation of cell adhesion and migration in lens development

Peggy S. Zelenka

Int. J. Dev. Biol. (2004) 48: 857-865

Expression of Frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development

Yongjuan Chen, Richard J.W. Stump, Frank J. Lovicu and John W. McAvoy

Int. J. Dev. Biol. (2004) 48: 867-877

Activated Ras induces lens epithelial cell hyperplasia but not premature differentiation

Lixing W. Reneker, Leike Xie, Li Xu, Venkatesh Govindarajan and Paul A. Overbeek

Int. J. Dev. Biol. (2004) 48: 879-888


Development of lens sutures

Jer R. Kuszak, Rebecca K. Zoltoski and Clifford E. Tiedemann

Int. J. Dev. Biol. (2004) 48: 889-902

Corneal development associated with eyelid opening

James D. Zieske

Int. J. Dev. Biol. (2004) 48: 903-911

Retina Differentiation

Genetic control of retinal specification and determination in Drosophila

Kartik S. Pappu and Graeme Mardon

Int. J. Dev. Biol. (2004) 48: 913-924

Genetics of photoreceptor development and function in zebrafish

Motokazu Tsujikawa and Jarema Malicki

Int. J. Dev. Biol. (2004) 48: 925-934

A moving wave patterns the cone photoreceptor mosaic array in the zebrafish retina

Pamela A. Raymond and Linda K. Barthel

Int. J. Dev. Biol. (2004) 48: 935-945

Neurotrophic regulation of retinal ganglion cell synaptic connectivity: from axons and dendrites to synapses

Susana Cohen-Cory and Barbara Lom

Int. J. Dev. Biol. (2004) 48: 947-956

New views on retinal axon development: a navigation guide

Fanny Mann, William A. Harris and Christine E. Holt

Int. J. Dev. Biol. (2004) 48: 957-964

Cell death in the developing vertebrate retina

Elena Vecino, María Hernández and Mónica García

Int. J. Dev. Biol. (2004) 48: 965-974

Ocular Stem Cells and Regeneration

A newt's eye view of lens regeneration

Panagiotis A. Tsonis, Mayur Madhavan, Emily E. Tancous and Katia Del Rio-Tsonis

Int. J. Dev. Biol. (2004) 48: 975-980


Ocular surface epithelial and stem cell development

J. Mario Wolosin, Murat T. Budak and M.A. Murat Akinci

Int. J. Dev. Biol. (2004) 48: 981-991

Retinal stem cells in vertebrates: parallels and divergences

Marcos A. Amato, Emilie Arnault and Muriel Perron

Int. J. Dev. Biol. (2004) 48: 993-1001

Retinal stem cells and regeneration

Ala Moshiri, Jennie Close and Thomas A. Reh

Int. J. Dev. Biol. (2004) 48: 1003-1014

Biopathology of Eye Development


Anterior segment development relevant to glaucoma

Douglas B. Gould, Richard S. Smith and Simon W.M. John

Int. J. Dev. Biol. (2004) 48: 1015-1029

Congenital hereditary cataracts

Jochen Graw

Int. J. Dev. Biol. (2004) 48: 1031-1044

Development and pathology of the hyaloid, choroidal and retinal vasculature

Magali Saint-Geniez and Patricia A. D'Amore

Int. J. Dev. Biol. (2004) 48: 1045-1058