The International Journal of Developmental Biology

Int. J. Dev. Biol. 62: 383 - 386 (2018)

Vol 62, Issue 6-7-8

Special Issue: Regeneration

Can broken hearts be mended? Ken Poss, a pioneer on heart regeneration research

Open Access | Interview | Published: 21 June 2018

Nadia Mercader*,1 and Florenci Serras*,2

1Institute of Anatomy, University of Bern, Bern, Switzerland and 2Department of Genetics, Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain


In 2002, Ken Poss discovered that zebrafish, at that time an emerging vertebrate model organism in basic research, were able to regenerate their heart upon resection of the ventricular apex. This finding set in motion a new field of research on heart regeneration, which has recently expanded in other model organisms including mammals. We interviewed Ken Poss to find out more about his motivation and vision for the future of tissue regeneration research.


heart regeneration, cardiomyocyte, fin regeneration, progenitor cell, organ regeneration, zebrafish

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