Int. J. Dev. Biol. 57: 197 - 200 (2013)
Special Issue: Male Germ Cells in Development & Tumors
Testicular germ cell tumors and related research from a historical point of view
Published: 30 May 2013
Abstract
In this brief overview of the history of testicular germ cell tumors, we touch upon the key events and personalities that have contributed to our current understanding of germ cell tumors in general, and those of the testis in particular. The intricacies of human germ cell tumor pathology and histogenesis have been elucidated in part by contributions in the field of experimental pathology and developmental biology. Correlation between clinical oncologic findings, pathology and experimental studies of germ cell tumors and related topics ushered the era of cellular and genetic engineering that have revolutionized contemporary cell and molecular biology.
Keywords
history, testis, germ cell tumor, teratoma, teratocarcinoma, embryonal carcinoma, embryonic stem cell