The cover shows the response to FGF16 of pluripotent cells explanted from Xenopus embryos. The explants shown at the top of the image have not been treated and have formed a ball of ciliated epidermis. When the pluripotent cells are exposed to FGF, the explants give rise to organoid-like structures that include mesodermal derivatives such as skeletal muscle, smooth muscle and fibroblasts surrounded by a layer of epidermis. The explants exhibit a threshold response to FGF as can be seen by the centre-bottom treated explant that has not been induced. For more details, see paper by Elsy et al. pp. 631-639 in the current issue.
Brinster Spermatogonial Stem Cell Transplantation 25th Anniversary Symposium
Int. J. Dev. Biol. (2019) 63: 573-578
Present status and expectation of aristaless-related homeobox (ARX) in endocrine pancreas
Int. J. Dev. Biol. (2019) 63: 579-587
Int. J. Dev. Biol. (2019) 63: 589-595
Int. J. Dev. Biol. (2019) 63: 597-604
Hedgehog signaling dynamics in mouse embryos determined by a bioluminiscent reporter
Int. J. Dev. Biol. (2019) 63: 605-613
Expression of primary cilia-related genes in developing mouse gonads
Int. J. Dev. Biol. (2019) 63: 615-621
Identification and expression analysis of zebrafish testis-specific gene 10 (tsga10)
Int. J. Dev. Biol. (2019) 63: 623-629
Int. J. Dev. Biol. (2019) 63: 631-639
