CHAP (Cytoskeletal Heart-enriched Actin-associated Protein) is encoded by a novel cardiac-enriched gene. The photograph shows a stage HH11 chick embryo expressing CHAP mRNA in the looping heart. In later stages, besides expression in the heart, CHAP is also expressed in the somites and muscle precursors of tongue, jaw, eye and limbs. For more information, see article by Van Eldik et al., pp. 645-651
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