Developmental stages of Purkinje cells in the cerebellum according to Santiago Ramón y Cajal (1852-1934). Top: the successive stages in the maturation of the dendritic tree are: the stellate phase (A), the phase of orientation and systematization of dendrites (B), the young Purkinje cell phase (C) and the adult phase (D). Below: photographs taken from Cajal´s original histological preparations stained with the Golgi method corresponding to: left, lack of orientation in the initial dendritic phase (new-born puppy); middle, the phase of systematization and orientation of dendrites (new-born puppy) (similar to B), and right, young Purkinje cell phase (from a young cat, almost adult) (similar to D). Cajal's drawing and microphotographs of the histological preparations are reproduced with the permission of the Inheritors of Santiago Ramón y Cajal. For further information, see García-López et al. pp. 1405-1417 in the current issue.
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