Int. J. Dev. Biol. 49: 79 - 83 (2005)

https://doi.org/10.1387/ijdb.041944cg

Vol 49, Issue 2-3

Special Issue: The Nogent Institute

L'École de Nogent: the contributions of Etienne Wolff and Nicole Le Douarin

Published: 1 May 2005

Charles Galperin*

Paris, France

Abstract

We retrace here the foundation of the "Nogent School". What were its main scientific orientations? Two fields of research dominated Etienne Wolff's work: Experimental Teratology and Intersexuality. Nicole Le Douarin's work , in one sense, started with a remarkable tool which is the quail / chick marker system. She applied this system to the study of in vivo migration of cells during embryonic life, i.e.neural crest cells and lymphoid progenitors. This article revisits some of these fundamental aspects.

Keywords

experimental teratology, intersexuality,migration, differentiation, neural crest, Quail/ Chick