The axolotl urodele can regenerate its limbs after amputation, as is illustrated here in histological images. During the regeneration process a blastema grows; this is composed of many undifferentiated cells. Some but not all blastema cells exhibit multipotency; these are considered to be similar to limb bud cells in that limb developmental processes are recapitulated in the blastema in order to recreate the sectioned limb. For further details, see Satoh et al. pp. 605-612 (https://doi.org/10.1387/ijdb.180118as) in the current issue.
OPEN ACCESS
Nerve roles in blastema induction and pattern formation in limb regeneration
Int. J. Dev. Biol. (2018) 62: 605-612
OPEN ACCESS
Int. J. Dev. Biol. (2018) 62: 613-621
Int. J. Dev. Biol. (2018) 62: 623-629
FRET-based tension measurement across actin-associated mechanotransductive structures using Lima1
Int. J. Dev. Biol. (2018) 62: 631-636
Pkd2 deletion during embryo development does not alter mesonephric programmed cell senescence
Int. J. Dev. Biol. (2018) 62: 637-640
Int. J. Dev. Biol. (2018) 62: 641-645