The midkine (Mdk) protein is known to play important roles in neurogenesis. The gibel carp (Carassius auratus gibelio) version of this protein, known as CagMdkb has been cloned and characterized. Gibel carp embryos injected with wild type CagMdkb RNAs exhibit severe deficiencies including a reduction in the forebrain region and eye structure. These findings, together with others reported in the present paper indicate that CagMdkb plays an important role in fish neural development and head formation. For further details, see the paper by Yin et al. pp. 761-769.
Int. J. Dev. Biol. (2007) 51: 689-700
Int. J. Dev. Biol. (2007) 51: 701-706
DNA methylation state is preserved in the sperm-derived pronucleus of the pig zygote
Int. J. Dev. Biol. (2007) 51: 707-714
Int. J. Dev. Biol. (2007) 51: 715-721
An efficient method for isolation of murine bone marrow mesenchymal stem cells
Int. J. Dev. Biol. (2007) 51: 723-729
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Interleukin-2 induces the proliferation of mouse primordial germ cells in vitro
Int. J. Dev. Biol. (2007) 51: 731-738
Human conjunctival epithelial precursor cells and their progeny in 3D organotypic culture
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Developmental expression of CagMdkb during gibel carp embryogenesis
Int. J. Dev. Biol. (2007) 51: 761-769