The International Journal of Developmental Biology

Volume 50 > Issue 8

Cover Vol. 50 N. 8

Cover Legend

FGF (fibroblast growth factor) signalling between the limb bud mesenchyme and the apical ectodermal ridge (AER) is critical for limb patterning and growth. The AER is a specialized epithelium running around the tip of the limb bud and, as the cover picture shows, a gene encoding Flrt3 (fibronectin-leucine-rich transmembrane protein 3) is strongly expressed here and outlines the limb bud of stage HH20 chick embryos. Flrt3 has been suggested to regulate FGF signalling by physically interacting with FGF receptors and enhancing downstream signalling. For further details, see the paper by Smith et al. pp. 701-704 in the present issue.

Meeting Report

Eye development at the Houston "Fly Meeting"

Amit Singh

Int. J. Dev. Biol. (2006) 50: 659-663


Retinal ganglion cells: dying to survive

Marc B. Guerin, Declan P. McKernan, Colm J. O'Brien and Thomas G. Cotter

Int. J. Dev. Biol. (2006) 50: 665-674

Original Articles

Hox and ParaHox genes in Nemertodermatida, a basal bilaterian clade

Eva Jiménez-Guri, Jordi Paps, Jordi García-Fernández and Emili Saló

Int. J. Dev. Biol. (2006) 50: 675-679

Xtbx6r, a novel T-box gene expressed in the paraxial mesoderm, has anterior neural-inducing activity

Shigeharu Yabe, Shunsuke Tazumi, Jun Yokoyama and Hideho Uchiyama

Int. J. Dev. Biol. (2006) 50: 681-689

Technical Article

Visualization of primordial germ cells in vivo using GFP-nos1 3'UTR mRNA

Taiju Saito, Takafumi Fujimoto, Shingo Maegawa, Kunio Inoue, Minoru Tanaka, Katsutoshi Arai and Etsuro Yamaha

Int. J. Dev. Biol. (2006) 50: 691-700

Developmental Expression Patterns

The expression of Flrt3 during chick limb development

Terence G. Smith and Cheryll Tickle

Int. J. Dev. Biol. (2006) 50: 701-704

N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase expression during early mouse embryonic development

Ana-Marisa Salgueiro, Mário Filipe and José-António Belo

Int. J. Dev. Biol. (2006) 50: 705-708

Expression of Dlx5 and Dlx6 during specification of the elbow joint

Deborah Ferrari and Robert A. Kosher

Int. J. Dev. Biol. (2006) 50: 709-713