Axis formation in Xenopus req uires cortical rotation and mesoderm induction. In untreated embryos (left embryo in cover picture) cortical rotation shifts a dorsalizing activity towards the future dorsal side. The expression domains of nr3 and sia, which are activated via a process ass ociated with the region of the prospective mesoderm in the marginal zone. In UV-treated em bryos (right embryo) cortical rotation is blocked and dorsal-specific genes are activated in cells at the vegetal pole after MBT. Due to the lack of overlap between their expressio n domain and the marginal zone, the expression of genes such as gsc cannot be maint ained outside the mesodermal region. Under these conditions, no organizer can form and no axis can be established. For details see "Cortical rotation is required for the correct s patial expression of nr3, sia and gsc in Xenopus embryos" by M edina et al. in this issue.
Int. J. Dev. Biol. (1997) 41: 643-653
Int. J. Dev. Biol. (1997) 41: 655-666
Int. J. Dev. Biol. (1997) 41: 667-677
Int. J. Dev. Biol. (1997) 41: 679-690
Int. J. Dev. Biol. (1997) 41: 691-698
Developmental expression of H3.3A variant histone mRNA in mouse.
Int. J. Dev. Biol. (1997) 41: 699-703
A 3' remote control region is a candidate to modulate Hoxb-8 expression boundaries.
Int. J. Dev. Biol. (1997) 41: 705-714
Targeted over-expression of FGF in chick embryos induces formation of ectopic neural cells.
Int. J. Dev. Biol. (1997) 41: 715-723
Int. J. Dev. Biol. (1997) 41: 725-732
Shh, Fgf4 and Hoxd gene expression in the mouse limb mutant hypodactyly.
Int. J. Dev. Biol. (1997) 41: 733-736
Contralateral efferent neurons can be detected in the hindbrain outside of rhombomere 4.
Int. J. Dev. Biol. (1997) 41: 737-739
Int. J. Dev. Biol. (1997) 41: 741-745
Local origin of cells in FGF-4 - induced outgrowth of amputated chick wing bud stumps.
Int. J. Dev. Biol. (1997) 41: 747-750