Int. J. Dev. Biol. 33: 407 - 416 (1989)

Vol 33, Issue 4

Two dimensional gel human protein databases offer a systematic approach to the study of cell proliferation and differentiation

Published: 15 December 1989

J E Celis, B Gesser, K Dejgaard, B Honoré, H Leffers, P Madsen, A Andersen, B Basse, A Celis and J B Lauridsen

Institute of Medical Biochemistry, Aarhus University, Denmark.

Abstract

Human cellular protein databases have been established using computer-analyzed 2D gel electrophoresis. These databases, which include information on various properties of proteins, offer a global approach to the study of regulation of cell proliferation and differentiation. Furthermore, thanks to the advent of microsequencing the databases make it possible to directly link protein and DNA information.