TY - JOUR TI - Debatable issues. Interview with L Wolpert and A GarcĂ­a-Bellido. AU - Ghysen, Alain T2 - The International Journal of Developmental Biology AB - This paper reports a discussion between Antonio Garcia-Bellido and Lewis Wolpert about a number of questions raised by Alain Ghysen. The questions follow, in reverse order, the subjects dealt with in this issue: first the principles (are there unifying principles of development?), then questions dealing with evolution (why are patterns conserved?) and with the homeotic genes (what is their function?), then the cell biology of development (who is controlling actual morphogenesis?), and the generation and evolution of patterns (what makes development so reproducible and how does it change from one species to another?) and finally about the genetics of cell determination and specification (how does a cell measure its position?). Obviously the discussion did not provide any firm answers to any of these questions. Perhaps more importantly, it provides a vivid picture of two contrasting ways of thinking about developmental problems. PY - 1998 VL - 42 IS - 3 SP - 511 EP - 518 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/9654040 Y2 - 2024/12/22/08:06:25 ER -