TY  - JOUR
TI  - TLR7 expression patterns in mouse eye development and adult ocular tissues
AU  - Rasile, Marco
AU  - Sommariva, Michele
AU  - Menegola, Elena
AU  - Di Renzo, Francesca
AU  - Anselmi, Martina
AU  - Sfondrini, Lucia
AU  - Barajon, Isabella
AU  - Arnaboldi, Francesca
T2  - The International Journal of Developmental Biology
AB  - Toll-Like Receptor 7 (TLR7) is recognized for its role in immune responses, particularly in detecting viral RNA. However, emerging evidence suggests that TLR7 may also contribute to ocular development. In this study, we assessed the expression pattern of TLR7 in various CD-1 mouse eye compartments during critical developmental stages, from embryonic day 12 to 16, as well as in adult tissues such as the cornea, pigmented epithelium, neural retina and lens. Our findings reveal a region-specific and time-dependent expression of TLR7, suggesting that it may play a role in the morphogenetic processes that shape the eye during intrauterine development.
PY  - 2025
DO  - 10.1387/ijdb.240229fa
VL  - 69
IS  - 2
SP  - 101
EP  - 107
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/240229fa
Y2  - 2025/12/22/14:26:09
ER  -