TY - JOUR TI - Development of the vertebrate small intestine and mechanisms of cell differentiation. AU - Dauca, M AU - Bouziges, F AU - Colin, S AU - Kedinger, M AU - Keller, M K AU - Schilt, J AU - Simon-Assmann, P AU - Haffen, K T2 - The International Journal of Developmental Biology AB - The intestinal epithelium represents an attractive biological model of differentiation from stem cells to highly differentiated epithelial cells, not only during particular developmental events depending upon the vertebrate species considered but also throughout adult life. The ontogenic maturation of the intestinal epithelium arises from both a programmed expression of specific genes and epigenetic influences mainly due to epithelial and mesenchymal interactions and hormonal participation. In the present paper we review the structural and functional changes that occur in the amphibian, avian and mammalian intestine during embryonic and/or post-embryonic development. Furthermore, we review the data concerning the mechanisms which control the cytodifferentiation of the intestinal epithelium. PY - 1990 VL - 34 IS - 1 SP - 205 EP - 218 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/2203458 Y2 - 2024/11/05/19:23:56 ER -