TY  - JOUR
TI  - RNA silencing pathways in plant development and defense
AU  - Kryovrysanaki, Nikoleta
AU  - James, Anthony
AU  - Tselika, Martha
AU  - Bardani, Eirini
AU  - Kalantidis, Kriton
T2  - The International Journal of Developmental Biology
AB  - RNA silencing refers to a conserved eukaryotic process and is regarded as one of the most important processes in plants, with the ability to regulate gene expression both transcriptionally and post-transcriptionally. Different classes of non-coding RNAs (ncRNAs) constitute key components of the RNA silencing pathways and play pivotal roles in modulating various biological processes as well as host-pathogen interactions. One of the most extensively studied classes of ncRNAs are the 20–24 nucleotide (nt) long microRNAs (miRNAs), which are core components of the endogenous gene silencing pathway. miRNAs act as negative regulators of endogenous gene expression through either mRNA-target cleavage, translational inhibition, or DNA methylation, and are inextricably linked to a plethora of developmental processes, such as leaf pattern formation as well as abiotic and biotic stress responses. In this review, we focus on the role of the RNA silencing pathways in the regulation of developmental processes as well as in the plant responses to biotic stress.
PY  - 2022
DO  - 10.1387/ijdb.210189kk
VL  - 66
IS  - 1-2-3
SP  - 163
EP  - 175
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/210189kk
Y2  - 2024/05/03/06:46:34
ER  -