TY - JOUR TI - RNA silencing pathways in plant development and defense AU - Kryovrysanaki, Nikoleta AU - James, Anthony AU - Tselika, Martha AU - Bardani, Eirini AU - Kalantidis, Kriton T2 - The International Journal of Developmental Biology AB - RNA silencing refers to a conserved eukaryotic process and is regarded as one of the most important processes in plants, with the ability to regulate gene expression both transcriptionally and post-transcriptionally. Different classes of non-coding RNAs (ncRNAs) constitute key components of the RNA silencing pathways and play pivotal roles in modulating various biological processes as well as host-pathogen interactions. One of the most extensively studied classes of ncRNAs are the 20–24 nucleotide (nt) long microRNAs (miRNAs), which are core components of the endogenous gene silencing pathway. miRNAs act as negative regulators of endogenous gene expression through either mRNA-target cleavage, translational inhibition, or DNA methylation, and are inextricably linked to a plethora of developmental processes, such as leaf pattern formation as well as abiotic and biotic stress responses. In this review, we focus on the role of the RNA silencing pathways in the regulation of developmental processes as well as in the plant responses to biotic stress. PY - 2022 DO - 10.1387/ijdb.210189kk VL - 66 IS - 1-2-3 SP - 163 EP - 175 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/210189kk Y2 - 2024/12/21/19:06:07 ER -