TY - JOUR TI - Inducing your neighbors to become like you: cell recruitment in developmental patterning and growth AU - Muñoz-Nava, LuisM. AU - Flores-Flores, Marycruz AU - Nahmad, Marcos T2 - The International Journal of Developmental Biology AB - Cell differentiation, proliferation, and morphogenesis are generally driven by instructive signals that are sent and interpreted by adjacent tissues, a process known as induction. Cell recruitment is a particular case of induction in which differentiated cells produce a signal that drives adjacent cells to differentiate into the same type as the inducers. Once recruited, these new cells may become inducers to continue the recruitment process, closing a feed-forward loop that propagates the growth of a specific cell-type population. So far, little attention has been given to cell recruitment as a developmental mechanism. Here, we review the components of cell recruitment and discuss its contribution to development in three different examples: the Drosophila wing, the vertebrate inner ear, and the mammalian thyroid gland. Finally, we posit some open questions about the role of cell recruitment in organ patterning and growth. PY - 2021 DO - 10.1387/ijdb.200127mn VL - 65 IS - 4-5-6 SP - 357 EP - 364 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/200127mn Y2 - 2024/10/11/05:08:54 ER -