TY  - JOUR
TI  - Post-translational modifications of HOX proteins, an underestimated issue
AU  - Draime, Amandine
AU  - Bridoux, Laure
AU  - Graba, Yacine
AU  - Rezsohazy, René
T2  - The International Journal of Developmental Biology
AB  - Post-translational modifications (PTMs) are important determinants which contribute to modulating the turn-over, intracellular localisation, molecular interactions and activity of most eukaryotic proteins. Such modifications and their consequences have been extensively examined for some proteins or classes of proteins. This is not the case for the HOX transcription factors which are crucial regulators of animal development. In this review, we provide a survey of the literature and data repositories pertaining to HOX-associated PTMs. This highlights that HOX proteins are also likely widely post-translationally modified, and defines HOX PTMs as an under-valued facet of their biology.
PY  - 2018
DO  - 10.1387/ijdb.180178rr
VL  - 62
IS  - 11-12
SP  - 733
EP  - 744
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/180178rr
Y2  - 2024/05/04/16:21:46
ER  -