TY  - JOUR
TI  - Segmentation of the chick central and peripheral nervous systems
AU  - Keynes, Roger
AU  - Cook, Geoffrey
T2  - The International Journal of Developmental Biology
AB  - The chick embryo has provided a prominent model system for the study of segmental patterning in the nervous system. During early development, motor and sensory axon growth cones traverse the anterior/rostral half of each somite, so avoiding the developing vertebral components and ensuring separation of spinal nerves from vertebral bones. A glycoprotein expressed on the surface of posterior half-somite cells confines growth cones to the anterior half-somites by a contact repulsive mechanism. Hindbrain segmentation is also a conspicuous feature of chick brain development. We review how its contemporary analysis was initiated in the chick embryo, and the advantages the chick system continues to provide in its detailed elucidation at both molecular and neural circuit levels.
PY  - 2018
DO  - 10.1387/ijdb.170297rk
VL  - 62
IS  - 1-2-3
SP  - 177
EP  - 182
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/170297rk
Y2  - 2024/11/23/10:25:58
ER  -