TY  - JOUR
TI  - Teratomas produced from human pluripotent stem cells xenografted into immunodeficient mice - a histopathology atlas
AU  - Damjanov, Ivan
AU  - Andrews, PeterW.
T2  - The International Journal of Developmental Biology
AB  - This atlas illustrates the microscopic features of tumors produced from human pluripotent stem cells (hPSCs) xenografted into immunosuppressed mice, according to the generally accepted protocols for performing this teratoma assay of stem cell pluripotency. Microphotographs depict various hematoxylin and eosin (H&E) stained tissues derived from all three embryonic germ layers (ectoderm, mesoderm and endoderm). The appearance of persistent hPSC in teratomas is also described with special emphasis on the morphogenesis of embryoid bodies and yolk sac components surrounding them. The use of immunohistochemistry for analyzing hPSC-derived teratomas is also illustrated.
PY  - 2016
DO  - 10.1387/ijdb.160274id
VL  - 60
IS  - 10-11-12
SP  - 337
EP  - 419
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/160274id
Y2  - 2024/11/05/13:21:04
ER  -