TY  - JOUR
TI  - Aurora-A: an expedition to the pole of the spindle in <I>Xenopus</I> egg extracts 
AU  - Kubiak, JacekZ.
AU  - Prigent, Claude
T2  - The International Journal of Developmental Biology
AB  - The aim of this short review is to describe the contribution of Xenopus laevis egg extracts to the discovery and understanding of the regulation and function of the serine/threonine kinase Aurora-A. The power of these extracts to recapitulate cell cycle events makes them a precious tool to decipher complex biological processes at the molecular level, including the mechanisms that affect Aurora-A (post-translational modifications) and mechanisms in which Aurora-A plays a crucial role (bipolar spindle assembly). We focus on the results obtained in cell-free extracts, but we also give an updated overview of Aurora A functions found in other systems.
PY  - 2016
DO  - 10.1387/ijdb.160189jk
VL  - 60
IS  - 7-8-9
SP  - 255
EP  - 261
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/160189jk
Y2  - 2024/11/21/18:31:35
ER  -