TY - JOUR TI - Expression of Sox genes in tooth development AU - Kawasaki, Katsushige AU - Kawasaki, Maiko AU - Watanabe, Momoko AU - Idrus, Erik AU - Nagai, Takahiro AU - Oommen, Shelly AU - Maeda, Takeyasu AU - Hagiwara, Nobuko AU - Que, Jianwen AU - Sharpe, PaulT. AU - Ohazama, Atsushi T2 - The International Journal of Developmental Biology AB - Members of the Sox gene family play roles in many biological processes including organogenesis. We carried out comparative in situ hybridization analysis of seventeen sox genes (Sox1-14, 17, 18, 21) during murine odontogenesis from the epithelial thickening to the cytodifferentiation stages. Localized expression of five Sox genes (Sox6, 9, 13, 14 and 21) was observed in tooth bud epithelium. Sox13 showed restricted expression in the primary enamel knots. At the early bell stage, three Sox genes (Sox8, 11, 17 and 21) were expressed in pre-ameloblasts, whereas two others (Sox5 and 18) showed expression in odontoblasts. Sox genes thus showed a dynamic spatio-temporal expression during tooth development. PY - 2015 DO - 10.1387/ijdb.150192ao VL - 59 IS - 10-11-12 SP - 471 EP - 478 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/150192ao Y2 - 2024/11/05/13:20:12 ER -