TY  - JOUR
TI  - Intracellular localizations of the Dead End protein in <I>Xenopus</I> primordial germ cells
AU  - Taguchi, Ayaka
AU  - Watanabe, Kenji
AU  - Orii, Hidefumi
T2  - The International Journal of Developmental Biology
AB  - We investigated the intracellular localization of Xenopus Dead end protein (Dnd1) in primordial germ cells during early development by expressing the tagged protein in transgenic Xenopus embryos, with the germ plasm visualized. Dnd1 initially localized to the germ plasm in the cortex, moved to the perinuclear region together with the germ plasm after the midblastula transition, and then entered the nucleus. Using Dnd1 deletion mutants, we identified two distinct but overlapping regions of Dnd1 that were responsible for localization to either the germ plasm or nucleus. These Dnd1 regions appeared to function in primordial germ cell- and stage-specific manners.
PY  - 2014
DO  - 10.1387/ijdb.140308ho
VL  - 58
IS  - 10-11-12
SP  - 793
EP  - 798
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/140308ho
Y2  - 2024/11/21/18:44:00
ER  -