TY - JOUR TI - Developmental biology of the leech Helobdella AU - Weisblat, DavidA. AU - Kuo, Dian-Han T2 - The International Journal of Developmental Biology AB - Glossiphoniid leeches of the genus Helobdella provide experimentally tractable models for studies in evolutionary developmental biology (Evo-Devo). Here, after a brief rationale, we will summarize our current understanding of Helobdella development and highlight the near term prospects for future investigations, with respect to the issues of: D quadrant specification; the transition from spiral to bilaterally symmetric cleavage; segmentation, and the connections between segmental and non-segmental tissues; modifications of BMP signaling in dorsoventral patterning and the O-P equivalence group; germ line specification and genome rearrangements. The goal of this contribution is to serve as a summary of, and guide to, published work. PY - 2014 DO - 10.1387/ijdb.140132dw VL - 58 IS - 6-7-8 SP - 429 EP - 443 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/140132dw Y2 - 2024/11/21/17:58:21 ER -