TY  - JOUR
TI  - Adaptive mechanisms controlling uterine spiral artery remodeling during the establishment of pregnancy
AU  - Soares, MichaelJ.
AU  - Chakraborty, Damayanti
AU  - Kubota, Kaiyu
AU  - Renaud, StephenJ.
AU  - Rumi, M. A. Karim
T2  - The International Journal of Developmental Biology
AB  - Implantation of the embryo into the uterus triggers the initiation of hemochorial placentation. The hemochorial placenta facilitates the acquisition of maternal resources required for embryo/fetal growth. Uterine spiral arteries form the nutrient supply line for the placenta and fetus. This vascular conduit undergoes gestation stage-specific remodeling directed by maternal natural killer cells and embryo-derived invasive trophoblast lineages. The placentation site, including remodeling of the uterine spiral arteries, is shaped by environmental challenges. In this review, we discuss the cellular participants controlling pregnancy-dependent uterine spiral artery remodeling and mechanisms responsible for their development and function.
PY  - 2014
DO  - 10.1387/ijdb.140083ms
VL  - 58
IS  - 2-3-4
SP  - 247
EP  - 259
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/140083ms
Y2  - 2024/11/05/13:20:08
ER  -