TY - JOUR TI - Uterine natural killer cells as modulators of the maternal-fetal vasculature AU - Matson, BrookeC. AU - Caron, KathleenM. T2 - The International Journal of Developmental Biology AB - Precise and local control of the innate immune system within the placenta is an essential component for achieving a normal and healthy pregnancy. One of the most abundant immune cells of the placenta is a subpopulation of natural killer (NK) cells that profusely populates the uterine decidua during early pregnancy. Uterine NK (uNK) cells and trophoblast cells of the placenta communicate both directly and indirectly to contribute to the critical process of spiral artery remodeling. Here, we discuss recent findings that expand our knowledge of uNK cell-trophoblast cell crosstalk and the important role it plays in the maternal vascular adaptation to pregnancy. PY - 2014 DO - 10.1387/ijdb.140032kc VL - 58 IS - 2-3-4 SP - 199 EP - 204 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/140032kc Y2 - 2024/12/14/04:11:57 ER -