TY  - JOUR
TI  - Nerve-dependent expression of c-myc protein during forelimb regeneration of Xenopus laevis froglets.
AU  - Lemaître, J M
AU  - Mechali, M
AU  - Geraudie, J
T2  - The International Journal of Developmental Biology
AB  - The consequences of denervation on the expression of c-myc protein have been analyzed on the regenerating forelimb of young froglets of Xenopus laevis. The level of c-myc expression, low in control limbs and enhanced in the regenerate, is transiently increased after a three-hour total denervation. For this protein, the level of expression is not a function of the quantity of nerve in the regenerate. Four days after denervation, c-myc signal is back to its base level observed in the regenerate. A different pattern of expression is obtained for an S phase marker (PCNA protein) taken as a control in the same experimental conditions. The data presented here show that the nervous system normally exerts a negative control on the expression of c-myc and PCNA proteins in the limb regenerate of Xenopus.
PY  - 1992
VL  - 36
IS  - 4
SP  - 483
EP  - 489
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/1363522
Y2  - 2024/12/22/15:12:53
ER  -