TY  - JOUR
TI  - Mechanisms of cranial placode assembly
AU  - Breau, Marie Anne
AU  - Schneider-Maunoury, Sylvie
T2  - The International Journal of Developmental Biology
AB  - Cranial placodes are transient ectodermal structures contributing to the paired sensory organs and ganglia of the vertebrate head. Placode progenitors are initially spread and intermixed within a continuous embryonic territory surrounding the anterior neural plate, the so-called pan-placodal region, which progressively breaks into distinct and compact placodal structures. The mechanisms driving the formation of these discrete placodes from the initial scattered distribution of their progenitors are poorly understood, and the implication of cell fate changes, local sorting out or massive cell movements is still a matter of debate. Here, we discuss different models that could account for placode assembly and review recent studies unraveling novel cellular and molecular aspects of this key event in the construction of the vertebrate head.
PY  - 2014
DO  - 10.1387/ijdb.130351mb
VL  - 58
IS  - 1
SP  - 9
EP  - 19
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/130351mb
Y2  - 2024/04/24/07:19:30
ER  -