TY - JOUR TI - Carcinoma in situ -from clinical observation to a paradigm shift for testicular carcinogenesis AU - Toppari, Jorma T2 - The International Journal of Developmental Biology AB - Carcinoma in situ in the testis has its origin in the fetal gonad and leads to testicular cancer in young adulthood. It can be detected in a testicular biopsy and treated with irradiation, which can preserve testosterone production of the man. These are the key findings of Niels E. Skakkebaek that changed our view of testicular tumourigenesis during the last fifty years. These and other findings are discussed in this interview-based review of testicular germ cell cancer. PY - 2013 DO - 10.1387/ijdb.130145jt VL - 57 IS - 2-3-4 SP - 221 EP - 223 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/130145jt Y2 - 2024/12/14/05:07:28 ER -