TY  - JOUR
TI  - OCT4 and the acquisition of oocyte developmental competence during folliculogenesis
AU  - Zuccotti, Maurizio
AU  - Merico, Valeria
AU  - Belli, Martina
AU  - Mulas, Francesca
AU  - Sacchi, Lucia
AU  - Zupan, Blaz
AU  - Redi, CarloAlberto
AU  - Prigione, Alessandro
AU  - Adjaye, James
AU  - Bellazzi, Riccardo
AU  - Garagna, Silvia
T2  - The International Journal of Developmental Biology
AB  - The role that the transcription factor OCT4 plays during oocyte growth is yet unknown. In this review, we summarise the data on its potential role in the acquisition of oocyte developmental competence in the mouse. These studies describe the presence in MII oocytes and 2-cell embryos of an OCT4 transcriptional network that might be part of the molecular signature of maternal origin on which the inner cell mass and the embryonic stem cell-associated pluripotency is assembled and shaped. The Oct4-gene regulatory network thus provides a connection between eggs, early preimplantation embryos and embryonic stem cells.
PY  - 2012
DO  - 10.1387/ijdb.120174mz
VL  - 56
IS  - 10-11-12
SP  - 853
EP  - 858
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/120174mz
Y2  - 2024/11/05/13:20:19
ER  -