TY  - JOUR
TI  - Extensive conservation of sequences and chromatin structures in the bxd polycomb response element among Drosophilid species.
AU  - Dellino, Gaetano I
AU  - Tatout, Christophe
AU  - Pirrotta, Vincenzo
T2  - The International Journal of Developmental Biology
AB  - The Polycomb Response Element (PRE) is the nucleation site for the Polycomb silencing complexes. The sequences responsible for the recruitment of the components of the Polycomb complex are not well understood. A comparison of the bxd PRE sequences from several different Drosophila species shows that some changes have occurred during phylogeny but large blocks of sequence are conserved after a divergence of some 60 million years. We compare the PRE sequences, the sites of some known PRE binding proteins, the conservation of DNasel hypersensitive sites and relate them to the sequence of the Ultrabithorax promoter which these PREs regulate.
PY  - 2002
VL  - 46
IS  - 1
SP  - 133
EP  - 141
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/11902674
Y2  - 2024/11/05/17:18:27
ER  -