TY  - JOUR
TI  - Peptide signaling in <I>Hydra</I>
AU  - Fujisawa, Toshitaka
AU  - Hayakawa, Eisuke
T2  - The International Journal of Developmental Biology
AB  - Peptides play a number of crucial roles as signaling molecules in metazoans. In order to elaborate a more complete picture of the roles played by peptides in a single organism, we launched the “Hydra Peptide Project”. For this project, we used Hydra magnipapillata, a species belonging to Cnidaria, one of the most basal metazoan phyla, and using a peptidomic approach, we systematically identified a number of peptide signaling mole-cules, their encoding genes and their functions. In this article, we report the peptides isolated from Hydra and other cnidarians, as well as their synthesis, processing and release from the cells to the target. Possible peptide signaling pathways are overviewed and finally we dis-cuss the evolution of the peptide signaling system.
PY  - 2012
DO  - 10.1387/ijdb.113477tf
VL  - 56
IS  - 6-7-8
SP  - 543
EP  - 550
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/113477tf
Y2  - 2024/11/05/15:23:00
ER  -