TY  - JOUR
TI  - Small RNA pathways in <I>Schmidtea mediterranea</I>
AU  - Resch, AlissaM.
AU  - Palakodeti, Dasaradhi
T2  - The International Journal of Developmental Biology
AB  - Planarians are bilaterally symmetrical fresh water organisms capable of regenerating body parts from small fragments following bodily injury. Planarians possess a specialized population of pluripotent cells called neoblasts, which are responsible for their unique regenerative ability. The study of planarian stem cell biology and regeneration has traditionally focused on the transcription factors and proteins that regulate signal transduction pathways. New evidence shows that small RNA molecules are important players in stem cell function and regeneration, yet little is known about the exact nature of their regulatory roles during the regenerative process. In this review, we discuss biogenesis of microRNAs and piwiRNAs and their functional role in key developmental pathways in vertebrates and invertebrates with an emphasis on recent studies on planarian small RNA pathways.
PY  - 2012
DO  - 10.1387/ijdb.113436ar
VL  - 56
IS  - 1-2-3
SP  - 67
EP  - 74
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/113436ar
Y2  - 2024/12/31/05:44:22
ER  -