TY - JOUR TI - Making mesoderm--upstream and downstream of Xbra. AU - Smith, J C T2 - The International Journal of Developmental Biology AB - The mesoderm of the amphibian embryo is formed through an inductive interaction in which cells of the vegetal hemisphere of the embryo act on overlying equatorial cells. My laboratory is studying the Brachyury gene, which plays a key role in this interaction, being both necessary and sufficient for normal mesoderm formation. In this article I describe our attempts to understand how Xenopus Brachyury (Xbra) is activated in the right cells at the right time, and then to understand how Xbra exerts its effects. PY - 2001 VL - 45 IS - 1 SP - 219 EP - 224 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/11291849 Y2 - 2024/12/04/10:03:56 ER -