TY  - JOUR
TI  - Introducing the Spemann-Mangold organizer: experiments and insights that generated a key concept in developmental biology.
AU  - Sander, K
AU  - Faessler, P E
T2  - The International Journal of Developmental Biology
AB  - The "organizer paper", published by Hans Spemann and Hilde Mangold in 1924, initiated a new epoch in developmental biology. Also it marked the climax of Spemann's life-long research which began at the end of the nineteenth century. This introduction retraces some of the steps by which Spemann arrived at the organizer concept: The problem of amphibian lens induction including the so-called lens controversy, the early constriction experiments creating double headed malformations, and the homeo- and heteroplastic transplantations during gastrula stages of the newt. Furthermore this paper will--based on historical documents--repudiate some objections raised to the contribution of Spemann and Hilde Mangold to the discovery and interpretation of the organizer effect.
PY  - 2001
VL  - 45
IS  - 1
SP  - 1
EP  - 11
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/11291840
Y2  - 2024/11/23/11:41:43
ER  -