TY  - JOUR
TI  - Igf2 imprinting in development and disease.
AU  - Reik, W
AU  - Constancia, M
AU  - Dean, W
AU  - Davies, K
AU  - Bowden, L
AU  - Murrell, A
AU  - Feil, R
AU  - Walter, J
AU  - Kelsey, G
T2  - The International Journal of Developmental Biology
AB  - Igf2 is one of the first imprinted genes discovered and occupies a centre stage in the study of imprinting. This is because it has dramatic effects on the control of fetal growth, it is involved in growth disorders and in cancer, it interacts with products of other imprinted genes, and its imprinting status is under complex regulation in a cluster of tightly linked imprinted genes. Here we review briefly the key features of Igf2 imprinting in normal development and in disease, and hope to show what a fascinating subject of study this gene and its biology provides.
PY  - 2000
VL  - 44
IS  - 1
SP  - 145
EP  - 150
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/10761859
Y2  - 2024/11/05/17:16:20
ER  -