TY  - JOUR
TI  - Developmental tumours, early differentiation and the transforming growth factor beta superfamily.
AU  - Mummery, C L
AU  - van den Eijnden-van Raaij, A J
T2  - The International Journal of Developmental Biology
AB  - Embryonal carcinoma and embryonic stem cells have been very useful models for identifying some of the factors that regulate differentiation in early mammalian development. Here, we present a brief history of their original isolation and characterization and of their later introduction into the Hubrecht Laboratory. We illustrate in a review their contribution to our current understanding of the function of transforming growth factor beta and ligands binding to the receptors of a related factor, activin, in development with some of our own work.
PY  - 1999
VL  - 43
IS  - 7
SP  - 693
EP  - 709
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/10668979
Y2  - 2024/11/21/18:44:00
ER  -