TY  - JOUR
TI  - Zebrafish embryo, a tool to study tumor angiogenesis
AU  - Tobia, Chiara
AU  - De Sena, Giulia
AU  - Presta, Marco
T2  - The International Journal of Developmental Biology
AB  - Zebrafish (Danio rerio) represents a powerful model system in cancer research. Recent observations have shown the possibility to exploit zebrafish to investigate tumor angiogenesis, a pivotal step in cancer progression and target for anti-tumor therapies. Experimental models have been established in zebrafish adults, juveniles, and embryos, each one with its own advantages and disadvantages. Novel genetic tools and high resolution in vivo imaging techniques are also becoming available in zebrafish. It is anticipated that zebrafish will represent an important tool for chemical discovery and gene targeting in tumor angiogenesis. This review focuses on the recently developed tumor angiogenesis models in zebrafish, with particular emphasis to tumor engrafting in zebrafish embryos.
PY  - 2011
DO  - 10.1387/ijdb.103238ct
VL  - 55
IS  - 4-5
SP  - 505
EP  - 509
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/103238ct
Y2  - 2024/11/21/17:43:42
ER  -