TY  - JOUR
TI  - The use of the orthotopic model to validate antivascular therapies for cancer
AU  - Loi, Monica
AU  - Di Paolo, Daniela
AU  - Becherini, Pamela
AU  - Zorzoli, Alessia
AU  - Perri, Patrizia
AU  - Carosio, Roberta
AU  - Cilli, Michele
AU  - Ribatti, Domenico
AU  - Brignole, Chiara
AU  - Pagnan, Gabriella
AU  - Ponzoni, Mirco
AU  - Pastorino, Fabio
T2  - The International Journal of Developmental Biology
AB  - The orthotopic model reproduces aspects of the tumour microenvironment and emulates a number of important biological features of cancer progression, angiogenesis, metastasis and resistance. Due to its parallels with human cancer, the model can be used to evaluate therapeutic responses to various therapies. This review outlines the importance of using the orthotopic implantation of tumour cells in mice models for evaluating the effectiveness of antivascular therapies.
PY  - 2011
DO  - 10.1387/ijdb.103230ml
VL  - 55
IS  - 4-5
SP  - 547
EP  - 555
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/103230ml
Y2  - 2024/11/05/15:26:17
ER  -