TY  - JOUR
TI  - The placenta as a haematopoietic organ
AU  - Ottersbach, Katrin
AU  - Dzierzak, Elaine
T2  - The International Journal of Developmental Biology
AB  - The recent description of the placenta as a tissue rich in haematopoietic stem and progenitor cells has not only opened up a whole new line of investigation into how haematopoiesis is regulated in this unique mammalian tissue, but has also resulted in the revisiting of long-standing and yet unanswered questions about the significance of having multiple haematopoietic organs during development. Due to its remarkable capacity for haematopoietic stem/progenitor cell expansion, the study of placental haematopoiesis is also of obvious clinical interest. In the following pages, we summarise what is currently known about the haematopoietic regulatory processes in the murine placenta and describe our most recent data demonstrating that the human placenta, like its murine counterpart, is also a source of haematopoietic stem and progenitor cells throughout development.
PY  - 2010
DO  - 10.1387/ijdb.093057ko
VL  - 54
IS  - 6-7
SP  - 1099
EP  - 1106
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/093057ko
Y2  - 2024/11/05/11:20:18
ER  -