TY - JOUR TI - Masculinization of XX Drosophila transgenic flies expressing the Ceratitis capitata DoublesexM isoform AU - Saccone, Giuseppe AU - Salvemini, Marco AU - Pane, Attilio AU - Polito, LinoC. T2 - The International Journal of Developmental Biology AB - The Doublesex (DSX) transcription factor regulates somatic sexual differentiation in Drosophila melanogaster. Female and male isoforms (DSXF and DSXM) are produced due to sex-specific RNA splicing. Here we show that in the distantly related dipteran Ceratitis capitata, the DSXM male-specific isoform is conserved and able to induce masculinization of both somatic and germline tissues when ectopically expressed in XX Drosophila transgenic individuals. PY - 2008 DO - 10.1387/ijdb.082657gs VL - 52 IS - 8 SP - 1051 EP - 1057 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/082657gs Y2 - 2024/11/21/23:12:32 ER -