TY  - JOUR
TI  - Dicer inactivation causes heterochronic retinogenesis in <i>Xenopus laevis</i> 
AU  - Decembrini, Sarah
AU  - Andreazzoli, Massimiliano
AU  - Barsacchi, Giuseppina
AU  - Cremisi, Federico
T2  - The International Journal of Developmental Biology
AB  - Maturation of miRNAs by dicer is required in vertebrates for normal neural development. Here we report that dicer inactivation in Xenopus affects cell cycle progression, survival and timing of the generation of retinal cells, resulting in small retinas with lamination defects. In particular, dicer inactivation delays the exit from the cell cycle and the translation of key genes of late neurogenesis, highlighting a crucial role of miRNAs in retinal development.
PY  - 2008
DO  - 10.1387/ijdb.082646sd
VL  - 52
IS  - 8
SP  - 1099
EP  - 1103
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/082646sd
Y2  - 2024/11/05/15:24:09
ER  -