TY  - JOUR
TI  - Cloning and developmental expression of the <i>soxB2</i> genes, <i>sox14</i> and <i>sox21</i>, during <i>Xenopus laevis</i> embryogenesis
AU  - Cunningham, DoreenD.
AU  - Meng, Zhuo
AU  - Fritzsch, Bernd
AU  - Casey, Elena Silva
T2  - The International Journal of Developmental Biology
AB  - The Sox family of transcription factors is thought to regulate gene expression in a wide variety of developmental processes. Here we describe the cloning of the X. laevis orthologs of the SoxB2 family of transcription factors, sox14 and sox21. In situ hybridization revealed that sox14 expression is restricted to the hypothalamus, dorsal thalamus, the optic tectum, a region of the somatic motornucleus in the midbrain and hindbrain, the vestibular nuclei in the hindbrain and a discrete ventral domain in the developing spinal cord. In contrast to the limited expression domain of sox14, sox21 is found throughout the developing central nervous system, including the olfactory placodes, with strongest expression at the boundary between the midbrain and hindbrain.
PY  - 2008
DO  - 10.1387/ijdb.082586dc
VL  - 52
IS  - 7
SP  - 999
EP  - 1004
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/082586dc
Y2  - 2024/12/27/03:46:57
ER  -