TY  - JOUR
TI  - Concentrations of TATA box-binding protein (TBP)-type genes affect chordamesodermal gene expression
AU  - Goto, Toshiyasu
AU  - Keller, Ray
AU  - Asashima, Makoto
T2  - The International Journal of Developmental Biology
AB  - The TATA box-binding protein (TBP) is an essential component of transcription initiation complexes of all three eukaryotic RNA polymerases. Recent knockdown studies revealed that basic transcription factors are essential not only for gene transcription but also for regulating specific gene expression. However, the mechanism of and the effect by regulation of TBP expression are unknown during early embryogenesis. Here we show that the alteration of concentration of each TBP-type gene affected mutually one another's expression, suggesting that an optimal ratio of concentrations of TBP-type genes induce expression of specific genes.
PY  - 2008
DO  - 10.1387/ijdb.072467tg
VL  - 52
IS  - 4
SP  - 371
EP  - 375
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/072467tg
Y2  - 2024/12/04/19:49:02
ER  -