TY  - JOUR
TI  - Expression of zinc transporter family genes in <I>Dictyostelium</I>
AU  - Sunaga, Nobuya
AU  - Monna, Meri
AU  - Shimada, Nao
AU  - Tsukamoto, Mai
AU  - Kawata, Takefumi
T2  - The International Journal of Developmental Biology
AB  - Regulation of the zinc ion concentration is physiologically important to control the activities of a variety of cellular molecules. A BLAST search against a conserved domain of known zinc transporters identified twelve putative zinc transporter family genes in the Dictyostelium genome. Phylogenetic analysis revealed the presence of three zinc transporter subfamilies in Dictyostelium. One subfamily of proteins, consisting of the ZntA-D proteins, has weak homology to the STAT3-inducible LIV-1 protein. In addition, in situ hybridization revealed that the zntA-D genes are expressed in the pstAB cells, this expression being absent in the Dd-STATa null mutant. Thus, Dd-STATa may control stalk cell differentiation through some members of the zinc transporter family genes during Dictyostelium development.
PY  - 2008
DO  - 10.1387/ijdb.072389ns
VL  - 52
IS  - 4
SP  - 377
EP  - 381
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/072389ns
Y2  - 2024/11/05/19:25:40
ER  -